THE COINCIDENCE OF GLUCOSE-6-PHOSPHATE DEHYDROGENASE DEFICIENCY AND HEMOGLOBIN S GENE IN ÇUXUROVA PROVINCE, TURKEY

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Abstract
A total of 1,582 subjects from 10 villages of different ethnic populations were screened for glucose-6-phosphate dehydrogenase (G5PD deficiency (GdB-, Mediterranean variant) and hemoglobin S gene, and the coincidence of both abnormalities was determined. Although the prevalence of both abnormalities was found to be highest in an Eti-Turk group living in the Tarsus area, coincidence was not significant. In a single village of Adana Eti-Turks, however, coincidence was found to be significant, although neither the frequency of G5PD deficiency nor the existence of hemoglobin S gene was highest in that village.