REMISSIONS IN THYROTOXICOSIS AFTER DISCONTINUING THIOURACIL

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Abstract
A review of the literature has failed to reveal information which might serve to evaluate thiouracil as a possible form of treatment for permanent cure of thyrotoxicosis. The main reason for this is that too few patients have been followed for a sufficiently long period to warrant definite conclusions. The drug is now released for general distribution, and most physicians have the impression that it has no other use than as a preoperative form of therapy. Since a review of our series of 80 patients treated with thiouracil for over two months revealed a very definite pattern of behavior, we considered that enough data were now at hand to justify a few important tentative conclusions that might be helpful as a guide in the treatment of thyrotoxicosis with this preparation. REVIEW OF THE LITERATURE Apparently Palmer1 is the only author who has differentiated the nodular from the non-nodular toxic

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