Renal Carcinoma: Computer Analysis of 96 Patients Treated by Nephrectomy

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Abstract
Computer analysis of 109 items of pathologic, clinical and survival data from 96 patients with renal carcinoma treated by nephrectomy with or without adjuvant therapy between 1956 and 1976 was performed. The combined 1, 5 and 10 yr calculated survival rates for potentially curable non-metastatic renal carcinoma (stages I, II and III, provided the regional lymph nodes were not involved) were 95, 61 and 47%, respectively, compared to 1, 5 and 10 yr survival rates of 61, 5 and 0%, respectively, for stage IV tumors. The cytoplasmic appearance (clear or granular) was not a significant microscopic feature relevant to survival of the patient but the grade of the tumor was predictive of the outcome of disease. Other features of renal carcinoma, particularly invasion of the renal vein and, to a lesser degree, perinephric fat, were not as prognostically significant in this series. The clinical, radiologic, pathologic and survival data of this group of patients are analyzed.