New Insights into the Mechanism of the McMurry Reaction

Abstract
Not only pinacolate intermediates appear in McMurry reactions of aliphatic ketones R2CO (R = Me, Et, iPr) with MCl4Li(Hg) (M = Ti, U) [Eq. (1)]. Rather, carbenoid species must also be considered. This conclusion was drawn from an exact analysis of the reaction products as well as control experiments with pinacol derivatives. equation image

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