Simultaneous transient erythroblastopenia and agranulocytosis: IgG‐mediated inhibition of erythrogranulopoiesis
- 1 February 1987
- journal article
- case report
- Published by Wiley in European Journal of Haematology
- Vol. 38 (2) , 200-203
- https://doi.org/10.1111/j.1600-0609.1987.tb01162.x
Abstract
We report a case of simultaneous transient erythroblastopenia and agranulocytosis recovering spontaneously. In vitro study using autologous bone marrow cells after recovery demonstrated IgG‐mediated inhibition of both erythropoiesis and gran‐ulopoiesis but not megakaryopoiesis. The inhibitory activity disappeared shortly after remission. These findings suggest that IgG‐mediated inhibition of hematopoiesis may be pathogenetic for transient bone marrow failure of the patient.Keywords
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