Primary Affective Disorders and HLA Antigens

Abstract
In 125 patients with various types of primary affective [manic depressive] disorders, 27 HLA antigens of the A, B and C loci were examined. Bw40 occurred more frequently in the primary form (20.83% vs. 7.64% in controls) and Cw4 in the unipolar form (25%) and, in disease in general, 16% vs. 9.58% in controls. Following correction, these differences are statistically insignificant.

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