Mechanism of DNA chain growth. I. Possible discontinuity and unusual secondary structure of newly synthesized chains.
- 1 February 1968
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 59 (2) , 598-605
- https://doi.org/10.1073/pnas.59.2.598
Abstract
Most of the recently synthesized portion of the chromosome can be obtained after denaturation as small DNA molecules with a sedimentation coefficient of about 10S in a variety of bacterial systems and in 1 bacteriophage system. This supports the mechanism that 2 daughter strands are synthesized in a discontinuous fashion. The secondary structure of the chromosomal region containing these newly synthesized chains may differ from that of ordinary double-stranded DNA.This publication has 16 references indexed in Scilit:
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