The Survival of Excitability, Energy Production and Energy Utilization of the Heart
- 1 November 1958
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation
- Vol. 18 (5) , 935-945
- https://doi.org/10.1161/01.cir.18.5.935
Abstract
The resistance of the whole heart to complete ischemia is greater than that of heart muscle slices. There is a great variability in the survival time of the respiratory enzymes and co-enzymes. Cardiac excitability is vulnerable to anoxia as illustrated by rapid changes in the membrane resting and action potential. The alterations may be closely related to changes in high-energy phosphate concentration. Energy utilization in heart muscle is quite resistant to anoxia. The chemical changes in heart muscle after death are discussed.Keywords
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