Principles of CDK regulation
- 9 March 1995
- journal article
- review article
- Published by Springer Nature in Nature
- Vol. 374 (6518) , 131-134
- https://doi.org/10.1038/374131a0
Abstract
As key regulators of the cell cycle, the cyclin-dependent kinases must be tightly regulated by extra- and intracellular signals. The activity of cyclin-dependent kinases is controlled by four highly conserved biochemical mechanisms, forming a web of regulatory pathways unmatched in its elegance and intricacy.Keywords
This publication has 85 references indexed in Scilit:
- The PCL2 (ORFD)-PHO85 Cyclin-Dependent Kinase Complex: a Cell Cycle Regulator in YeastScience, 1994
- Cell Cycle Control by a Complex of the Cyclin HCS26 (PCL1) and the Kinase PHO85Science, 1994
- Phosphate-Regulated Inactivation of the Kinase PHO80-PHO85 by the CDK Inhibitor PHO81Science, 1994
- A brain-specific activator of cyclin-dependent kinase 5Nature, 1994
- p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5Nature, 1994
- Phosphorylation of the Transcription Factor PHO4 by a Cyclin-CDK Complex, PHO80-PHO85Science, 1994
- Mammalian G1 cyclinsCell, 1993
- Control of the yeast cell cycle by the Cdc28 protein kinaseCurrent Opinion in Cell Biology, 1993
- The Role of p34 Kinases in the G1 to S-Phase TransitionAnnual Review of Cell Biology, 1992
- ANIMAL CELL CYCLES AND THEIR CONTROLAnnual Review of Biochemistry, 1992