Structure and evolution of the heavy chain from rat immunoglobulin E
Open Access
- 1 January 1982
- journal article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 10 (19) , 6041-6049
- https://doi.org/10.1093/nar/10.19.6041
Abstract
The nucleotide sequence of the rat ɛ-chain mRNA has been determined by sequencing cloned cDNA copies of the mRNA. The established sequence covers the coding region, the 3′-non coding region and most of the 5′ non-coding region. A comparison with the nucleotide sequence of the human ɛ-chain constant region reveals that C3 and C4 are the most highly conserved domains. The rat ɛ-chain contains a C-terminal decapeptide which is not present in the human counterpart.Keywords
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