Effect of 1-(2,4-dichlorobenzyl)-indazole-3-carboxylic acid on sperm tails in rhesus monkeys
- 1 March 1978
- journal article
- research article
- Published by Bioscientifica in Reproduction
- Vol. 52 (2) , 275-278
- https://doi.org/10.1530/jrf.0.0520275
Abstract
Large numbers of spermatozoa with bent or coiled tails were found in the ejaculates of rhesus monkeys treated with 1-(2,4-dichlorobenzyl-indazole-3-carboxylic acid (DICA) (50 or 500 mg/kg for various periods). The defect appeared only in spermatozoa in the cauda epididymidis and consisted of axoneme disarrangement and loss of fiber doublets. The coil was completely enclosed in a membrane. [DICA is a potential contraceptive agent.].This publication has 5 references indexed in Scilit:
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