Community-Based Interventions for Marginalized Populations

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Abstract
Combination antiretroviral therapy has led to dramatic reductions in morbidity and mortality among patients with HIV/AIDS, including those who present with advanced AIDS and very low CD4+ cell counts. Unfortunately, many HIV-infected persons have not realized the benefits of HAART because of difficulties in accessing care or an inability to adhere to medications. The majority of these persons are active substance users, have mental health disorders, or cope with social instability, such as homelessness [1–3]. It is now recognized that innovative approaches are needed to increase access and adherence to HAART, especially among these hard-to-reach populations [4].