HLA‐B SNA antigen: a BW6 associated B locus antigen belonging to the B5 CREG

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Abstract
A new B locus antigen has been found in members of two unrelated families and in a patient originating from Morocco belonging to the Berber population. A complete analysis has been performed with antisera from the 9th and 10th IHWS defining the B5 CREG antigens. Serology, absorption experiments and family studies indicate that SNA antigen is a Bw6 associated subtype of B5 antigen closely related to but clearly distinct from each of the B5 CREG antigens. One‐dimensional isoelectric focusing study (1D‐IEF) confirms that the SNA antigen precipitates as a B locus gene product and has an isoelectric point identical to that of B w52 and one of the charge variants of B51.