Erythromycin and Tetracycline Hydrochloride in the Treatment of Non-Gonococcal Urethritis

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Abstract
Sixty-two previously untreated patients with non-gonococcal urethritis were treated with 6 g erythromycin and 58 previously untreated patients were given the same dose of tetracycline. Of the 57 erythromycin-treated cases followed, there were 13 failures (22.8%). Of the 52 tetracycline-treated cases followed, there were 9 failures (17.3%). When the results were accumulated to take into account differences in follow-up, the cumulative failure rate was 33.9% for those treated with erythromycin and 29.8% for those treated with tetracycline. Patients in whom the symptoms had been present for more than 1 week apparently responded better than those in whom the symptoms had been present for 1 week or less. Side-effects were relatively few and mild.

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