Depolarization- and Ionophore-Induced Release of Octacosa Somatostatin from Stalk Median Eminence Synaptosomes
- 21 August 1981
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 213 (4510) , 913-915
- https://doi.org/10.1126/science.6114560
Abstract
Species of somatostatin of higher molecular weight were present in the nerve terminals (synaptosomes) of ovine stalk median eminences and were released by depolarizing stimuli. One of these species was identified as the biologically active molecule octacosa somatostatin. Octacosa somatostatin appears therefore to be secreted into the hypothalamic-hypophyseal system, supporting the concept of a role for this peptide in regulating pituitary hormone secretion.This publication has 15 references indexed in Scilit:
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