Fermentable sugar in normal urine

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Abstract
Fermentable sugar was absent from normal fasting urine. After glucose ingestion in the morning under fasting conditions no increased amount of fermentable sugar could be detected. Half the medical students studied showed small amounts of fermentable sugar in the post-prandial afternoon urine. Fermentable urinary sugar was seen in 2 subjects after orange juice, honey and invert sugar, in 2 others after large amounts of fruit. Fifty or 25 gm. of pure fructose produced the same degree of glycosuria, given in the morning or at about 4:00 P.M. Afternoon glycosuria occurred frequently, i.e., 50 gm. glucose at 4:00 P.M. produced glycosuria in persons showing none under the fasting conditions of the morning test. This was least likely to occur after a noon meal high in carbohydrate, always followed a noon meal rich in protein and frequently a high fat noon meal. Blood-sugar curves at 4:00 P.M. possessed a higher peak than the corresponding fasting morning tolerance curves, often rising above the usual renal threshold for sugar and accounting for afternoon glycosuria. A high carbohydrate noon meal gave rise to the lowest blood-sugar curve after 50 gm. glucose at 4:00 P.M. and high fat and high protein noon meals gave high peak curves.

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