LYMPHOCYTE BLAST TRANSFORMATION AND ANTIBODY RESPONSES AFTER VACCINATION WITH INACTIVATED MUMPS VIRUS VACCINE
- 1 November 1981
- journal article
- research article
- Published by Wiley in Acta Pathologica Microbiologica Scandinavica Section C Immunology
- Vol. 89C (1-6) , 303-310
- https://doi.org/10.1111/j.1699-0463.1981.tb02704.x
Abstract
Mumps antibody response and the development of cell‐mediated immunity (CMI) to mumps antigen as assayed by the lymphocyte blast transformation method were studied after immunization with an inactivated mumps vaccine in seven sero‐negative and ten sero‐positive subjects. The transformation response of peripheral blood lymphocytes to mumps antigen generally appeared by 20 weeks post vaccination and reached levels found in sero‐positive subjects years after mumps infection. There was no clear‐cut correlation between the magnitude of blast transformation and antibody responses.Keywords
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