Pilot Study for Large‐Scale Plasma Procurement Using Automated Plasmapheresis
- 5 March 1983
- journal article
- research article
- Published by Wiley in Vox Sanguinis
- Vol. 44 (3) , 143-150
- https://doi.org/10.1111/j.1423-0410.1983.tb01876.x
Abstract
A pilot study for large-scale automated plasmapheresis using the Hemonetics Model 50 machine was undertaken in the Yorkshire Region of the UK to determine the viability of such a program for national self-sufficiency in fresh plasma procurement for factor VIII concentrate production. The study was designed to resolve 3 areas of concern: donor safety and recruitment, cost analysis and the choice of anticoagulant for optimum factor VIII yields. Large-scale automated plasmapheresis could safely and economically produce high-quality source plasma necessary for national self-sufficiency.This publication has 11 references indexed in Scilit:
- HIGH-YIELD METHOD OF PRODUCTION OF FREEZE-DRIED PURIFIED FACTOR VIII BY BLOOD BANKSThe Lancet, 1981
- A New Technique for the Collection of Plasma: Machine PlasmapheresisTransfusion, 1981
- Intermediate purity factor VIII production utilizing a cold-insoluble globulin techniqueThrombosis Research, 1980
- Preparation of Improved Cryoprecipitated Factor VIII ConcentrateVox Sanguinis, 1980
- A Factor VIII Concentrate of Intermediate Purity and Higher PotencyTransfusion, 1979
- Improved Yields of Factor VIII from Heparinized PlasmaVox Sanguinis, 1979
- Volume Limitations of PlasmapheresisVox Sanguinis, 1977
- The estimation of citrate in serum and urine using a citrate lyase techniqueClinica Chimica Acta; International Journal of Clinical Chemistry, 1973
- THE OSMOTIC RESISTANCE (FRAGILITY) OF HUMAN RED CELLS 1Journal of Clinical Investigation, 1947
- Über ein phosphatübertragendes gärungsfermentBiochimica et Biophysica Acta, 1947