Pancreatic Atrophy Apparently Secondary to Hydrochlorothiazide

Publisher Website
Google Scholar
Abstract
THE recent publication by Cornish et al.1 of a clinical and experimental study relating chlorothiazide to abnormal pancreatic secretion and inflammatory and necrotizing changes in the mouse pancreas provides a highly probable solution to a recent case of severe pancreatic atrophy and chronic pancreatitis found at autopsy in this hospital in a nine-and-a-half-year-old boy. Stowens2 has stated that acute hemorrhagic pancreatitis has not been described in children, and MacGregor3 does not mention the subject in her textbook. The finding of an advanced atrophy of the pancreas and an associated chronic pancreatitis in this age group is of interest, per se. . . .