Studies on the conformation and dynamics of the C8-substituted guanlne adduct of the carcinogen acetytaminofluorene; model for a possible Z-DNA modified structure
Open Access
- 12 November 1984
- journal article
- research article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 12 (21) , 8219-8233
- https://doi.org/10.1093/nar/12.21.8219
Abstract
The structure of an adduct between guanine and the carcinogen acetylaminofluorene has been examined in the solid state by X-ray crystallography, and in solution by NMR techniques. The observed conformations have been compared with predictions from energy calculations and their relevance to models of adducts with DNA has been examined.Keywords
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