Abstract
Hydroxyapatite (HA) discs were treated for 1 min with fluoride solutions of varying concentrations and pH. The calcium fluoride and fluoridated hydroxyapatite (FHA) formed were analyzed independently of each other following their separation in molar KOH. Only the more intimately associated FHA affected the rate of acid dissolution of HA and its level of formation and the reduction in acid dissolution rate of HA were both linearly related to the logarithm of the ionic fluoride level in the treatment solution following 1 min pretreatement. The benefit of using acidulated fluoride treatment of enamel [in humans] is questioned as neutral fluoride treatments of enamel mineral resulted in equivalent protection.

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