STUDIES ON STREPTOMYCES GRISEOCARNEUS AND THE PRODUCTION OF HYDROXYSTREPTOMYCIN
- 1 October 1951
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 62 (4) , 487-497
- https://doi.org/10.1128/jb.62.4.487-497.1951
Abstract
S. griseocarneus, isolated from soil in Japan, produces hydroxystreptomycin, which differs from commercial streptomycin by an additional O atom in the streptose portion of the molecule. Methods of production and in vitro activity of hydroxystreptomycin are discussed. Some peculiarities with regard to low antibiotic tolerance at the start and at the completion of this fermentation are cited.Keywords
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