Azide Substitution at Mannose Derivatives. A Potential New Route to Glucosamine Derivatives

Abstract
Since the pioneering work of Paulsen et al.1 on stereoselective coupling reactions of glucosamine derivatives, the azide function has found general application in carbohydrate chemistry as a nonparticipating masking group for amines. Although excellent results have been reported for the synthesis of α-coupled glucosamine derivatives, the preparation of the required 2-azido-2-deoxy- -glucopyranose is often laborious.1c