Differential effects of exercise on serum lipid and lipoprotein levels seen with changes in body weight. A meta-analysis

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Abstract
Studies (95) conducted between Sept. 1955 and Oct. 1983 measuring changes in human serum lipid and lipoprotein levels in response to exercise training were analyzed using meta-analysis. Change in body weight during exercise training may confound observed serum lipid and lipoprotein level changes; thus, data from these studies were partitioned into those where subjects gained body weight, maintained body weight or lost body weight. Results showed differential changes in cholesterol, triglyceride, low-density lipoprotein-cholesterol (LDL-C), high-density lipoprotein-cholesterol and cholesterol/high-density lipoprotein-cholesterol level in the 3 body-weight categories. Where body weight did not change, cholesterol and LDL-C levels decreased significantly (7.3 mg/dl and 3.3 mg/dl, respectively). Where body weight decreased, cholesterol and LDL-C levels also decreased significantly (13.2 mg/dl and 11.1 mg/dl, respectively). However, with body-weight increase, cholesterol and LDL-C levels increased by 2.9 mg/dl and 3.0 mg/dl, respectively. Reductions in cholesterol and LDL-C levels were greatest when exercise training was combined with body-weight losses.

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