Inducible expression of insulin receptors on T lymphocyte clones.
Open Access
- 1 August 1982
- journal article
- research article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 156 (2) , 664-669
- https://doi.org/10.1084/jem.156.2.664
Abstract
Insulin receptors are expressed on the surface of some mouse T cell clones after specific antigenic stimulation. The insulin receptors on these lymphocytes are physicochemically similar to insulin receptors present on cells which express the receptors constitutively (adipocytes, hepatocytes, etc.). The kinetics of expression of insulin receptors on cloned, noncytotoxic T cells after specific antigenic stimulation closely parallels that of [3H]incorporation in such cultures.This publication has 13 references indexed in Scilit:
- Studies Utilizing Murine T Cell Clones Ir Genes, Ia Antigens and MLR Stimulating DeterminantsImmunological Reviews, 1981
- Rapid mixed lymphocyte culture testing by analysis of the insulin receptor on alloactivated T lymphocytes: implications for human tissue typing.Journal of Clinical Investigation, 1981
- A close relationship between cytotoxic T lymphocytes generated in the mixed lymphocyte culture and insulin receptor-bearing lymphocytes: Enrichment by density gradient centrifugationCellular Immunology, 1979
- The insulin receptor as a universal marker of activated lymphocytesEuropean Journal of Immunology, 1978
- Immunologic recognition of influenza virus-infected cellsCellular Immunology, 1977
- Membrane receptors for hormones and neurotransmitters.The Journal of cell biology, 1976
- A procedure for removing red cells and dead cells from lymphoid cell suspensionsJournal of Immunological Methods, 1975
- Insulin-Induced Augmentation of Lymphocyte-Mediated CytotoxicityScience, 1975
- Characteristics of the Human Lymphocyte Insulin ReceptorJournal of Biological Chemistry, 1973
- Emergence of Insulin Receptors on Human Lymphocytes During In Vitro TransformationProceedings of the National Academy of Sciences, 1972