Evidence for surface-coat localisation of a monoclonal antibody-isolated merozoite antigen ofBabesia divergens
- 1 January 1990
- journal article
- research article
- Published by Springer Nature in Zeitschrift Fur Parasitenkunde-Parasitology Research
- Vol. 76 (7) , 573-577
- https://doi.org/10.1007/bf00932564
Abstract
The localisation of monoclonal antibody-derived merozoite antigens ofBabesia divergens was examined using immunogold electron microscopy and immunoprecipitation of the monoclonal antibody with both biosynthetically and surface-labelled parasites. Immunogold labelling provided evidence that the antigens are components of the surface coat of the merozoite. Immunoprecipitation with biosynthetically labelled parasites showed the antigens to be of parasite origin, whereas surface labelling confirmed that the antigens form part of the surface coat.This publication has 12 references indexed in Scilit:
- A monoclonal antibody-derived antigen ofBabesia divergens: characterization and investigation of its ability to protect gerbils against virulent homologous challengeParasitology, 1989
- Identification of Babesia bovis merozoite surface antigens by using immune bovine sera and monoclonal antibodiesInfection and Immunity, 1988
- The precursor to major merozoite surface antigens: structure and role in immunity.1988
- A 46000 dalton Plasmodium falciparum merozoite surface glycoprotein not related to the 185000?195000 dalton schizont precursor molecule: isolation and characterizationZeitschrift Fur Parasitenkunde-Parasitology Research, 1988
- Merozoite surface coat precursor protein completely protects Aotus monkeys against Plasmodium falciparum malaria.Proceedings of the National Academy of Sciences, 1987
- Antibodies define multiple proteins with epitopes exposed on the surface of live Babesia bigemina merozoites.The Journal of Immunology, 1987
- A monoclonal antibody toBabesia divergenswhich inhibits merozoite invasionParasitology, 1987
- Immunization with a Plasmodium falciparum merozoite surface antigen induces a partial immunity in monkeys.Journal of Clinical Investigation, 1985
- Babesia bovis : Continuous Cultivation in a Microaerophilous Stationary Phase CultureScience, 1980