Effects of Inunction of Alpha-Estradiol on Testes and Thyroids of Albino Rats.
- 1 November 1949
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 72 (2) , 306-309
- https://doi.org/10.3181/00379727-72-17417
Abstract
Daily inunction for 24 days of 270 rat units of alpha-estradiol (Progynon D-H) to normal and castrated immature male rats produced noticeable changes in the thyroid glands and in the testes of the non-castrated males. The thyroid glands appeared, histologically, in a hypoactive state. They exhibited an increased colloid content and a low follicular epithelium and destruction to the follicles. The hypoactivity appeared greater in castrated rats than in the non-castrated. Descent of the testes in immature males was prevented by the alpha-estradiol.Keywords
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