Enantioselective Catalytic Borane Reductions of Achiral Ketones: Synthesis and Application of New Rigid Catalysts Prepared from (R)-Phenylglycine and (S)-Phenylalanine
- 1 August 1993
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 23 (15) , 2091-2099
- https://doi.org/10.1080/00397919308018602
Abstract
Exnantiocontrolled reduction of prochiral ketones with borane in the presence of homochiral amino alcohols 1 - 4 as enantioselective catalysts afforded the chiral corresponding secondary alcohols in moderate to high (55 to 88 %) optical yields.Keywords
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