OBSERVATIONS ON MACROPHAGE BEHAVIOR IN THE FIN OF XENOPUS LARVAE
Open Access
- 1 December 1953
- journal article
- other
- Published by University of Chicago Press in The Biological Bulletin
- Vol. 105 (3) , 490-495
- https://doi.org/10.2307/1538465
Abstract
1. The hormone intermedin was injected into Xenopus larvae to induce pigment cell expansion. In the expanded condition melanophores were cut and macrophage ingestion of melanin granules and cell fragments was observed. 2. Macrophages retained parts of the ingested pigment cells for from one to five weeks. However, in no instance were these macrophages observed to synthesize melanin or to exhibit the physiological characteristics of melanophores as judged by their responsiveness to intermedin. 3. Preliminary observations on the influence of intermedin on nucleated and non-nucleated fragments of melanophores suggest that the cytoplasm of these pigment cells requires the presence of the nucleus in order to respond to the expanding stimulus of this hormone.This publication has 4 references indexed in Scilit:
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- The development and morphology of the larva of the South African clawed toad, Xenopus laevis II. The hatching and the first‐ and second‐form tadpolesJournal of Morphology, 1945
- Neurohumors as Chromatophore ActivatorsProceedings of the American Academy of Arts and Sciences, 1940
- The pigmentary effector system. VI. The dual character of endocrine co-ordination in amphibian colour changeProceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character, 1931