THE EXISTENCE OF THE SITES HOMOLOGICAL TO THE REGULATORY SITE OF HEAT-SHOCK IN MOBILE GENETIC ELEMENTS

  • 1 January 1987
    • journal article
    • research article
    • Vol. 23  (12) , 2112-2119
Abstract
The results of contextual analysis of 13 different mobile genetical elemens (MGE) MDG1, MDG2, MDG3, MDG4, HOBO, P, F, MDG 17.6, H. M. S. Beagle, CIN1, BS1, TDD1, EV1 are presented. A search for regions revealing marked and statistically non-random homology with the consensus sequence of the heat-shock regulatory site (HSRS) has been carried out in these elements. Seven MGE (MDG1, MDG4, HOBO, P, CIN1, BS1, EV1) were shown to contain the regions of non-random homology with the HSRS consensus and the real HSRS. Evolutionary significance of connection between the environment and genetical cell system, based on the transcriptional activation of mobile genetical elements by heat-shock and some other factors, has been discussed.