Plasmodium inui, a Quartan-Type Malaria Parasite of Old World Monkeys Transmissible to Man

Abstract
A quartan-type parasite of Old World monkeys has been found infective to man by the bites of infected mosquitoes (Anopheles stephensi and/or A. maculatus) in 2 volunteers and by the inoculation of parasitized blood in 5 volunteers. The prepatent period in the sporozoite-induced infections was 31 and 56 days with parasitemia for 21 and 24 days, respectively. The blood-induced infections were patent for 10 to 26 days. A quartan fever pattern was well marked in 2 volunteers with maximum fever of 103.2 F. The incidence of chills was low. Parasitized blood from four of the volunteers when injected into clean rhesus monkeys produced typical infections.