The p38/Reactivating Kinase Mitogen-activated Protein Kinase Cascade Mediates the Activation of the Transcription Factor Insulin Upstream Factor 1 and Insulin Gene Transcription by High Glucose in Pancreatic β-Cells
Open Access
- 1 August 1997
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 272 (33) , 20936-20944
- https://doi.org/10.1074/jbc.272.33.20936
Abstract
No abstract availableKeywords
This publication has 37 references indexed in Scilit:
- SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin‐1Published by Wiley ,2000
- A comparison of the substrate specificity of MAPKAP kinase‐2 and MAPKAP kinase‐3 and their activation by cytokines and cellular stressFEBS Letters, 1996
- Cellular Stresses and Cytokines Activate Multiple Mitogen‐Activated‐Protein Kinase Kinase Homologues in PC12 and KB CellsEuropean Journal of Biochemistry, 1996
- Function of the Human Insulin Promoter in Primary Cultured Islet CellsJournal of Biological Chemistry, 1996
- PD 098059 Is a Specific Inhibitor of the Activation of Mitogen-activated Protein Kinase Kinase in Vitro and in VivoJournal of Biological Chemistry, 1995
- Transcriptional regulation of the human insulin gene is dependent on the homeodomain protein STF1/IPF1 acting through the CT boxes.Proceedings of the National Academy of Sciences, 1994
- A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteinsPublished by Elsevier ,1994
- Pancreatic beta cell line MIN6 exhibits characteristics of glucose metabolism and glucose-stimulated insulin secretion similar to those of normal isletsDiabetologia, 1993
- Human insulin gene enhancer‐binding proteins in pancreatic α and β cell linesFEBS Letters, 1993
- A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingAnalytical Biochemistry, 1976