Interference reflection microscopy of adhesion of Amoeba proteus

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Abstract
SUMMARY: A simple method of observing the adhesive behaviour of large cells by means of interference reflection microscope is described, and some observations of mono‐podial Amoeba proteus are presented. Amoebae may contact with the substratum at any point along the long axis of the cells. Points of contact are usually few, small and temporary. Frequently the cell surface within the contact points oscillates, changing the separation distance from the substratum.