Science Papers and Discussions: The Basis for "Sufficient of a Suitable Bacteriostatic" in Injections
- 1 December 1958
- journal article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 10 (Supplement) , 40T-46T
- https://doi.org/10.1111/j.2042-7158.1958.tb10380.x
Abstract
In the light of the relative lethal and inhibitory properties of several known bacteriostats, including those recommended in the B.P., along with some observations on their partitioning ratios between rubber and water, the requirements for “sufficient of a suitable bacteriostatic” are discussed, and various criteria are suggested. Attention is drawn particularly to the narrowness of the margin between effective lethal concentration and minimum inhibitory concentration of many bacteriostats and to the consequent need to prevent their loss by absorption into rubber, or through any other cause. Activity against mould spores as well as against resistant vegetative bacteria is also desirable.Keywords
This publication has 4 references indexed in Scilit:
- Losses of Bacteriostats from Injections in Rubber-Closed ContainersJournal of Pharmacy and Pharmacology, 1957
- Pseudomonas pyocyanea in CetrimideBMJ, 1957
- On the Maintenance of Sterility in Eye-DropsJournal of Pharmacy and Pharmacology, 1954
- Phenol as the Preservative in Insulin InjectionsJournal of Pharmacy and Pharmacology, 1954