Effect of Cyanide Poisoning on the Central Nervous System of Rats and Dogs.

Abstract
Prolonged cyanide poisoning in rats may cause cerebral changes in 10% of the animals. Daily injection of potassium thiocyanate similarly results in brain injury in 10% of rats. In the rat continuous administration of sodium nitrite does not produce lesions in the central nervous system. In dogs cyanide poisoning with or without the nitrite-thiosulfate therapy does not induce abnormal behavior. When they die from the poisoning, their brains usually show a normal appearance.

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