Effects of Inanition, Protein Depletion and Repletion on Serum Lactic Acid Dehydrogenase Levels in Rats.

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Abstract
The effects of inanition, protein depletion and repletion upon serum lactic acid dehydrogenase (SLD), total serum protein and hematocrit values have been determined in adult, male Sprague-Dawley rats. Significant increases in concentration of SLD concomitant with decreases in serum protein levels followed inanition and protein depletion. Upon repletion, subnormal SLD values occurred in groups fed a diet containing 17% or more of protein. Serum protein values for the groups were significantly increased. The results are discussed with respect to possible causes for observed changes.