Antibody-directed enzyme prodrug therapy (ADEPT): a review
- 1 July 1997
- journal article
- review article
- Published by Elsevier in Advanced Drug Delivery Reviews
- Vol. 26 (2-3) , 151-172
- https://doi.org/10.1016/s0169-409x(97)00032-x
Abstract
No abstract availableKeywords
This publication has 83 references indexed in Scilit:
- Poly(ethylene glycol)-Doxorubicin Conjugates Containing .beta.-Lactamase-Sensitive LinkersBioconjugate Chemistry, 1995
- Tumour regressions with novel prodrugs in antibody-directed enzyme prodrug therapy (ADEPT)European Journal Of Cancer, 1994
- Novel analogues of CB 1954: Their potential use in antibody directed enzyme prodrug therapy (ADEPT)European Journal Of Cancer, 1994
- Tumor targeting: Activation of prodrugs by enzyme-monoclonal antibody conjugatesTrends in Biotechnology, 1994
- Analysis of a conjugate between anti-carcinoembryonic antigen monoclonal antibody and alkaline phosphatase for specific activation of the prodrug etoposide phosphateCancer Immunology, Immunotherapy, 1992
- Ablation of human choriocarcinoma xenografts in nude mice by antibody-directed enzyme prodrug therapy (ADEPT) with three novel compoundsEuropean Journal of Cancer and Clinical Oncology, 1991
- Activation of Methotrexate Prodrugs by Enzyme/Monoclonal Antibody ConjugatesPteridines, 1991
- Antibody-penicillin-V-amidase conjugates kill antigen-positive tumor cells when combined with doxorubicin phenoxyacetamideCancer Immunology, Immunotherapy, 1990
- Selective Cytotoxicity of Carboxypeptidase-activated Methotrexate ex-PeptidesPteridines, 1989
- CB 1954 (2,4-dinitro-5-aziridinyl benzamide) becomes a DNA interstrand crosslinking agent in Walker tumour cellsBiochemical and Biophysical Research Communications, 1986