POTASSIUM CHANGES IN THE FUNCTIONING HEART UNDER CONDITIONS OF ISCHEMIA AND OF CONGESTION

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Abstract
In amytalized cats samples of coronary venous blood were obtained some min. after ligation of both coronary arterial stems. In each of 9 animals the coronary venous blood showed a marked increase in K content. In contrast, a 20-min. period of venous congestion produced by ligating all the major cardiac veins caused no significant rise in the K content of the coronary venous blood. The expts. demonstrate that myocardial asphyxia leads to a liberation of K. The possible significance of this finding is discussed with reference to heart failure in clinical cases and also in relation to the chem. origin of visceral pain.

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