The Pleiotropic Effects of Natural AAV Infections on Liver-directed Gene Transfer in Macaques
Open Access
- 1 January 2010
- journal article
- Published by Elsevier in Molecular Therapy
- Vol. 18 (1) , 126-134
- https://doi.org/10.1038/mt.2009.245
Abstract
No abstract availableKeywords
This publication has 40 references indexed in Scilit:
- Systematic Evaluation of AAV Vectors for Liver directed Gene Transfer in Murine ModelsMolecular Therapy, 2010
- Evasion of Immune Responses to Introduced Human Acid α-Glucosidase by Liver-Restricted Expression in Glycogen Storage Disease Type IIMolecular Therapy, 2005
- Comparison of the ability of adeno-associated viral vectors pseudotyped with serotype 2, 5, and 8 capsid proteins to mediate efficient transduction of the liver in murine and nonhuman primate modelsMolecular Therapy, 2005
- Sustained correction of disease in naive and AAV2-pretreated hemophilia B dogs: AAV2/8-mediated, liver-directed gene therapyBlood, 2005
- Early Steps of Clathrin-Mediated Endocytosis Involved in Phagosomal Escape of Fcγ Receptor-Targeted AdenovirusJournal of Virology, 2005
- Clades of Adeno-Associated Viruses Are Widely Disseminated in Human TissuesJournal of Virology, 2004
- AAV2 Vector Harboring a Liver-Restricted Promoter Facilitates Sustained Expression of Therapeutic Levels of α-Galactosidase A and the Induction of Immune Tolerance in Fabry MiceMolecular Therapy, 2004
- Adeno-associated viruses undergo substantial evolution in primates during natural infectionsProceedings of the National Academy of Sciences, 2003
- Muscle-Specific Promoters May Be Necessary for Adeno-Associated Virus-Mediated Gene Transfer in the Treatment of Muscular DystrophiesHuman Gene Therapy, 2001
- Persistent and therapeutic concentrations of human factor IX in mice after hepatic gene transfer of recombinant AAV vectorsNature Genetics, 1997