DNA-binding studies with 6BT and 5I: implications for DNA-binding/carcinogenicity and DNA-binding/mutagenicity correlations
- 1 March 1988
- journal article
- research article
- Published by Elsevier in Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
- Vol. 198 (1) , 61-68
- https://doi.org/10.1016/0027-5107(88)90040-1
Abstract
No abstract availableKeywords
This publication has 17 references indexed in Scilit:
- Deficiencies in the covalent binding idnex (CBI) for expressing in vivo binding to DNA with respect to predicting chemical carcinogenicity: A proposal for a target-organ binding indexMutation Research Letters, 1987
- The use of in vivo-like concentrations of chemicals for validation of in vitro short-term genotoxicity assays - an in vivo equivalent dose conceptMutagenesis, 1987
- The disposition and in vivo covalent binding to liver DNA of the monoazodyes 6-(p-dimethylaminophenylazo)benzothiazole (6BT) and 5-(p-dimethylaminophenylazo) indazole (51) after administration to the ratCarcinogenesis: Integrative Cancer Research, 1986
- Mutagenicity to Salmonella of four derivatives of the azo mutagen 5I: some implications for structure—activity databases and the evaluation of combinations of mutagensMutagenesis, 1986
- An assessment of the in vivo rat hepatocyte DNA-repair assayMutation Research/Genetic Toxicology, 1985
- The possible role of azoreduction in the bacterial mutagenicity of 4-dimethylaminoazobenzene (DAB) and 2 of its analogues (6BT and 5I)Mutation Research/Genetic Toxicology, 1983
- A review of the genotoxicity of food, drug and cosmetic colours and other azo, triphenylmethane and xanthene dyesMutation Research/Reviews in Genetic Toxicology, 1982
- Limitations of Metabolic Activation Systems Used with in Vitro Tests for CarcinogensScience, 1980
- Carcinogenic activity of analogs of p-dimethylaminoazobenzene. IX. Activity of the quinoxaline and indazole analogsJournal of Medicinal Chemistry, 1969
- Carcinogenic activity of analogs of p-dimethylaminoazobenzene. VI. Activity of the benzimidazole and benzthiazole analogsJournal of Medicinal Chemistry, 1968