A model of protein conformational substates
- 1 June 1985
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 82 (11) , 3670-3672
- https://doi.org/10.1073/pnas.82.11.3670
Abstract
Many proteins have been observed to exist in a large number of conformations that are believed to play an important role in their dynamics. A model of protein conformational substates that incorporates the ideas of frustration and disorder in analogy to glasses and spin glasses is proposed. Applications to x-ray diffraction, Mössbauer studies, and recombination experiments are discussed.This publication has 4 references indexed in Scilit:
- Conformational substates in a protein: structure and dynamics of metmyoglobin at 80 K.Proceedings of the National Academy of Sciences, 1982
- Dynamics of metmyoglobin crystals investigated by nuclear gamma resonance absorptionJournal of Molecular Biology, 1981
- Temperature-dependent X-ray diffraction as a probe of protein structural dynamicsNature, 1979
- Dynamics of ligand binding to myoglobinBiochemistry, 1975