The Effect of Fluid Deprivation, Antidiuretic Hormone and Forced Fluid Intake on 51‐Cr‐EDTA Clearance
- 12 January 1981
- journal article
- research article
- Published by Wiley in Acta Medica Scandinavica
- Vol. 210 (1-6) , 377-380
- https://doi.org/10.1111/j.0954-6820.1981.tb09834.x
Abstract
The effect of fluid deprivation, antidiuretic hormone [desmopressin] (DDAVP) and forced fluid intake on glomerular filtration rate (GFR) was studied in 41 healthy males by determining 51-Cr-EDTA clearance after a single bolus injection. GFR was the same on forced and on free fluid intake. A small, clinically insignificant decrease in GRF (-6.5%), compared to values on free fluid intake, was registered during the period of fluid deprivation plus DDAVP. There seem to be no objections to combining a clearance study with a concentrating ability test when screening groups of subjects with normal or near normal GFR.Keywords
This publication has 16 references indexed in Scilit:
- Studies on Kidney Function in Subjects Exposed to Organic SolventsActa Medica Scandinavica, 1981
- Studies on Kidney Function in Subjects Exposed to Organic SolventsActa Medica Scandinavica, 1981
- Reference values for51Cr-EDTA clearance as a measure of glomerular filtration rateScandinavian Journal of Clinical and Laboratory Investigation, 1981
- Urinary concentration test with desmopressin.BMJ, 1978
- A Simple Method for the Determination of Glomerular Filtration RateScandinavian Journal of Clinical and Laboratory Investigation, 1972
- Renal Function in Man during Transition from Hydropenia to Water Diuresis with Superimposed Mannitol LoadActa Physiologica Scandinavica, 1969
- Renal Inulin Clearance versus Total Plasma Clearance of51Cr-EDTAScandinavian Journal of Clinical and Laboratory Investigation, 1969
- Simultaneous 51Cr edetic acid, inulin, and endogenous creatinine clearances in 20 patients with renal disease.BMJ, 1968
- A clinical appraisal of the plasma concentration and endogenous clearance of creatinineThe American Journal of Medicine, 1962
- A TEST OF THE CAPACITY OF THE KIDNEY TO PRODUCE A URINE OF HIGH SPECIFIC GRAVITYArchives of internal medicine (1960), 1922