Retention and egg production ofMicrophallus pygmaeus in mice: the influence of the adrenal cortex
- 1 January 1986
- journal article
- research article
- Published by Springer Nature in Zeitschrift Fur Parasitenkunde-Parasitology Research
- Vol. 72 (4) , 479-485
- https://doi.org/10.1007/bf00927891
Abstract
Fewer adultMicrophallus pygmaeus are recovered from the small intestine of adrenalectomized male mice than from sham-operated counterparts. Preinfection intraperitoneal injection of 2 IU or 4 IU ACTH adaily for 7 days increases the initial primary worm burden in male mice. Preinfection intramuscular injection of 325 μg corticosterone daily for 7 days increases the initial worm burden and alters the subsequent rate of decline and duration of the primary infection. However, egg production is unaffected. The changes in parasite numbers are attributed to the immunosuppressive action of corticosterone.This publication has 19 references indexed in Scilit:
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