Familial late complement component (C6, C7) deficiency with chronic meningococcemia
- 1 July 1980
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of internal medicine (1960)
- Vol. 140 (7) , 929-933
- https://doi.org/10.1001/archinte.140.7.929
Abstract
Two patients with chronic meningococcemia were found to lack hemolytic complement, one because of C6 deficiency, the other because of C7 deficiency. In both cases family studies were consistent with inheritance of the deficiencies as non-HLA-linked, autosomal co-dominant traits. Functional studies showed the deficient sera to support monocyte chemotaxis but not phagocytosis or lysis of meningococci. Both patients have remained well following antibiotic treatment. (Arch Intern Med140:929-933, 1980)This publication has 9 references indexed in Scilit:
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