CHRONIC THYROTOXIC MYOPATHY:REPORT OF A CASE*

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Abstract
This report concerns a case of chronic thyrotoxic myopathy with marked progressive symmetrical muscular weakness and atrophy of the shoulder girdle. Abnormality of creatine-creatinine metabolism was prominent. Treatment with propylthiouracil resulted in dramatic reversal of the thyrotoxicosis with marked improvement of the myopathy and personality deviations. Supplemental treatment with methyl-testosterone was associated with complete remission of the myopathy and restoration of personality equilibrium. The syndrome of thyrotoxic myopathy is rare but clinically important because it can be confused with the usually fatal primary myopathies, especially progressive muscular atrophy.

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