Systemic Absorption of Gallbladder Sclerosing Agents in the Rabbit
- 1 May 1986
- journal article
- research article
- Published by Wolters Kluwer Health in Investigative Radiology
- Vol. 21 (5) , 396-399
- https://doi.org/10.1097/00004424-198605000-00005
Abstract
Remley KB, Cubberley DA, Watanabe AS, Nelson JA, Colby TV. Systemic absorption of gallbladder sclerosing agents in the rabbit: a preliminary study. The absorbed levels of ethanol or tetracycline, used as gallbladder sclerosing agents, were measured in the systemic blood circulation of 16 rabbits. The maximal systemic level of ethanol was 46 mg/dl and of tetracycline was 4.6 µg/ml after 30 minutes of gallbladder exposure. Comparable serum levels would be considered nontoxic in humans. As a gallbladder sclerosing agent, tetracycline (50 mg/cc) was slightly more effective than 95% ethanol exposed for either 15 or 30 minutes.Keywords
This publication has 2 references indexed in Scilit:
- Transcatheter Sclerosis of the Gallbladder in RabbitsInvestigative Radiology, 1985
- Obliteration of the Gallbladder Without Formal CholecystectomyArchives of Surgery, 1984