Plateletpheresis: A comparative study of six different protocols

Publisher Website
Google Scholar
Abstract
Six different protocols were employed in 710 plateletpheresis employing Haemonetics 30, Fenwal CS‐3000, IBM 2997 dual stage channel, IBM 2997 single‐stage channel, and Haemonetics V‐50 „surge pump”︁ method. When Haemonetics 30 and IBM 2997 single‐stage channel procedures were used, 5.4 to 5.9 × 1011 platelets were collected with significant leukocyte contamination (10.8 to 11.6 × 109). With Fenwal CS‐3000, dual‐stage channel of IBM 2997 and Haemonetics V‐50 „surge pump”︁ there was less leukocyte contamination in concentrates (0.3 to 0.9 × 109) as well as a lower platelet yield (3.4 to 4.3 × 1011). No difference in yield was observed when plateletpheresis was performed with ACD‐A or ACD‐B employing the single‐stage channel of IBM 2997. Paraesthesias was the most frequently seen side effect in donors, with a higher incidence when using ACD‐A and IBM 2997.