Blood and Liver Glutathione During Protein Deprivation.
- 1 January 1952
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 79 (1) , 57-59
- https://doi.org/10.3181/00379727-79-19271
Abstract
A protein-free diet reduced liver glutathione in rats to about 40% of its normal value within 1 to 2 days, but did not deplete blood glutathione. The labile 60% of the liver glutathione was lost completely before the liver xanthine oxidase was reduced more than 50%; the residual 40% of the liver glutathione was then retained while the remainder of the xanthine oxidase was lost. 85-90% of the glutathione in rat liver was present in the soluble supernatant fraction obtained by centrifuging an homogenate at 30,000 x g.Keywords
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