Synthesis of the neocarzinostatin chromophore A core diynene structure using an η2-hexacarbonyidicobalt mediated Aldol reaction
- 1 January 1991
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 7,p. 541-543
- https://doi.org/10.1039/c39910000541
Abstract
The monoketal of cyclopentene-1,3-dione was converted into the η2-Co2(CO)6 neocarzinostatin core 19 in six steps; oxidative decomplexation in the presence of cyclohexa-1,4-diene gave the cycloaromatized adduct 22.Keywords
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