Synergistic Inhibitory Effect of Zinc and Hexetidine on in vitro Growth and Acid Production of Streptococcus mutans

Abstract
The combined effect of Zn and hexetidine on Streptococcus mutans OMZ 176 growth and acid production was investigated in vitro. Since the minimum inhibitory and bactericidal concentration of zinc and hexetidine in combination was significantly, lower than when applied separately, a synergistic antimicrobial action was evident.